Dr. Nina Crowley and Cystic Fibrosis Dietitian Sara Hendrix discuss how new drugs for Cystic Fibrosis are revolutionizing health, longevity, and nutrition absorption, leading to a shift in health concerns. While malnutrition and underweight were historically primary issues, advancements in treatment have led to overweight and obesity becoming new challenges. Body composition, focusing on fat mass and fat-free mass, is now crucial for clinical outcomes. They also address the hurdles of physical activity, the psychological effects of weight gain, and the need to combat weight bias. The conversation concludes with the benefits of implementing body composition testing for CF patients.